The cees dekker Diaries
The cees dekker Diaries
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It had been only within the nineties though, when nanotechnology experienced advanced to your degree where solitary molecules could be manipulated, that the 1st experimental products began to look.
Within the very same time, the group of Paul McEuen, who was then centered for the University of California, Berkeley, confirmed related final results on ropes of bundled nanotubes. Based on the wrapping angle, nanotubes can are available metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed using scanning tunnelling spectroscopy experiments.
Non-equilibrium folding of person DNA molecules recaptured around 1000 occasions inside a sound condition nanopore
2010, designed a completely new way (‘wedging transfer’) to manipulate nanostructures; initial report of DNA translocation by means of graphene nanopores; and recognized hybrid nanopores by directed insertion of α-hemolysin into stable-point out nanopores
SMC complexes can move Bodily roadblocks bigger than their ring size, indicating a nontopological system for DNA loop extrusion
We use nanofabricated microfluidic constructions to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks which assess the fundamental function of spatial confinement in the molecular and cellular level. Our projects include the subsequent:
Dynamic ParB–DNA interactions initiate and manage a partition condensate for bacterial https://www.ceesdekker.net chromosome segregation
‘Sure, I have an understanding of folks were being shocked at enough time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to admit that it experienced become a bit bored, I didn’t study A lot any more. The sector went more into the appliance aspect, how you could integrate nanotubes into electronic circuits.
There was just one trouble though — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule level, conducting polymers had been truly not this sort of wonderful conductors, which was somewhat disappointing. We So broadened our perspective to test to uncover extra promising molecules.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
1999, initially measurement from the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for the new Luttinger description of interacting electrons in nanotubes
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It absolutely was a really exciting time, during which I obtained many support from Delft University of Know-how, where I was a professor at time, And that i begun several collaborations with molecular biologists. That assisted me understand lots.’